Clinical Proof: Thyroid Data & Patient Resources

Clinical Proof: Thyroid Data & Patient Resources

 AUTHOR: Kimberly Orbons, Naturopath, The Lucy Rose Clinic, Adelaide 3rd August 2016

 

For anyone who is interested in some further reading, resources and clinical studies, we are compiling the following list. Trustworthy, free to access information oh health based on clinical studies and Practitioners with years of experience and health education. Just click the link to enjoy! We have a whole host of free blogs which are great to browse too, and of course we can always email you a copy of our Free Thyroid Ebook. If you are looking for more personal advice and testing options please book at the clinic nearest to you.

We will build and extend this Thyroid health related resource periodically, so let us know if there is more info you need! Last updated in 3rd August 2016.

 

Untitle33dNUTRITIONAL INFORMATION

Iodine deficient areas linked to Hyperthyroidism/nodules in China, which shows that Iodine levels are essential for both hyper and hypo thyroidism associated with nodular growths. “Subclinical hyperthyroidism and overt hyperthyroidism are more likely to be prevalent in the iodine deficient areas than in the iodine excess or sufficient areas.”

Why Salt is not enough: Clearing the Iodine confusion by Pharmacist Suzy Cohen “There’s mass confusion and paranoia about iodine, and that’s what prompted me to write today’s article. It actually dawned on me last night (while talking to a person with Hashimoto’s thyroiditis) that iodine is used all over your body. She thought it was just used by your thyroid and read someone’s blog about it, and became very afraid to take it. It’s in salt, the “iodized” salt, but that is not nearly enough iodine for many of you.”

Increasing Iodine dosages to eliminate low dose iodine reactions: “I think that you have to take upwards of 100mg of iodine or higher for the body to make this. Because when I take 25mg, I have horrible detox symptoms, but when I take 100mg of iodine I feel normal. I think that at 100mg and up, the body makes delta-iodolactone, and this [is an] antioxidant . It’s the only thing that can account for the fact that people, who can’t take 25mgs without getting sick, can take 150mg without a problem”. A different perspective, with many patient comments saying they have experienced the same issues, being unable to slowly increase, but coping extremely well. (Please note, we are NOT recommending everyone suddenly jump up their Iodine, but it is good reading to hear other patients experiences and up and coming health info trends based on actual patient experiences)

Iron deficiency and suboptimal ferritin levels can reduce your thyroid hormone count in animal studies, and lower the enzyme activity of Thyroidperoxidase within Thyroid cells for hormone regulation!

The role of selenium, vitamin C, and zinc in benign thyroid diseases and of selenium in malignant thyroid diseases: Low selenium levels are found in subacute and silent thyroiditis and in papillary and follicular carcinoma. Thyroid Seleniumphysiology is closely related to oxidative changes. The aim of this controlled study was to evaluate the levels of nutritional anti-oxidants such as vitamin C, zinc (Zn) and selenium (Se), and to investigate any association of them with parameters of thyroid function and pathology including benign and malignant thyroid diseases.

Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium. Basically, taking any key thyroid nutrient by itself without full case assessment and proper treatment in dangerous. In this case study, it shows how selenium, a key thyroid nutrient may exacerbate hypothyroidism when and Iodine deficiency is present. And if that’s not enough about Selenium, here is some more extensive references to go along with it:

  1. Sunde RA. Selenium. In: Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler TR, eds. Modern Nutrition in Health and Disease. 11th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2012:225-37
  2. Kresser, C 2012, Selenium: The Missing Link for Treating Hypothyroidism? Available from http://chriskresser.com/selenium-the-missing-link-for-treating-hypothyroidism/ . [20 January 2016].
  3. Natural Hormone Health n.d. Is A Hormone Imbalance Causing Fatigue, Hot Flushes, Weight Gain, Low Sex Drive, Depression Or Anxiety? Available from: natural-hormone-health.com/hormone-imbalance.html . [21 January 2016].
  4. Lam, M 2012, Estrogen Dominance – Part 2, Adrenal Fatigue Center. Available from https://www.drlam.com/blog/estrogen-dominance-part-2/1781/ . [21 January 2016].
  5. Stop The Thyroid Madness 2005-2016, Selenium – What’s that? What’s it good for? Available from stopthethyroidmadness.com/selenium/ . [21 January 2016].
  6. University of Maryland Medical Center (UMMC) 2016, Selenium. Available from https://umm.edu/health/medical/altmed/supplement/selenium . [21 January 2016].
  7. Bembu n.d., 15 Foods Rich in Selenium for a Healthier Thyroid. Available from bembu.com/selenium-rich-foods . [21 January 2016].
  8. Terry EN, Diamond AM. Selenium. In: Erdman JW, Macdonald IA, Zeisel SH, eds. Present Knowledge in Nutrition. 10th ed. Washington, DC: Wiley-Blackwell; 2012:568-87
  9. Dennert G, Horneber M. Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients. Cochrane Database Syst Rev 2006:CD005037. [PubMed abstract]
  10. Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes: Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, DC, 2000.
  11. Marcocci C, Kahaly GJ, Krassas GE, Bartalena L, Prummel M, Stahl M, et al. Selenium and the course of mild Graves’ orbitopathy. N Engl J Med 2011;364:1920-31. [PubMed abstract]

'Salt Your Way to Health' by Dr David Brownstein

‘Salt Your Way to Health’ by Dr David Brownstein

SALT TYPES and  RESOURCES

Salt Your Way to Health: Book by Dr David Brownstein “For years, we have heard the following: A low-salt diet is healthy. There is no difference between table salt and sea salt. Low-salt products are better for you. These are the myths of salt. Dr. Brownstein will present the research on salt that will change the way you look at this vital substance”

Iodized salt found to be inefficient in correcting iodine levels in lactating women, a study assessing multiple countries and 42 clinical studies that cites “within the iodine deficiency range, indicating that iodine supplementation in daily prenatal vitamin/mineral supplements in lactating mothers is warranted”

 

Thyroid Data & Resources

Many medications suppress Thyroid metabolism, have a read about some here. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1070767/

What’s Blocking Your thyroid? Free tips from our Head Naturopath Kimberly Orbons in this 6min YouTube video

Checking your own Thyroid by Temperature According to Dr. Broda Barnes: A reading below the normal 98 (after adding 1 degree to under the arm temperature) strongly suggests hypothyroid. A reading above 98.2 may indicate hyperthyroidism (overactive thyroid). (For us Aussies: 98 °F = 36.67 °C The conversion formula is °C = 5/9 (°F – 32)

Herbs like Withania can increase Thyroid metabolism in 8 weeks: “Subtle changes in thyroid indices during a placebo-controlled study of an extract of Withania somnifera in persons with bipolar disorder”

 

DRUGS AND PHARMACEUTICALS

 

Avoid Dangerous Interactions When Taking Supplements, by Pharmacist Suzy Cohen 18/06/2015

“We are better off getting our nutrients from healthy foods and beverages, but dietary supplements can fill a nutritional gap.  It’s confusing to know when you should take certain nutrients, especially the minerals which can bind or “chelate” with a lot of different medications. It’s also difficult to time your supplements around meals and medications. 

Over the years, I’ve used my own vitamin list to help me remember when and how to take supplements.”

1.SLEEPING-TABLETS

The Statin Disaster, book by Dr David Brownstein “Statins are the most profitable drugs in the history of Big Pharma. Statins fail to prevent or treat heart disease for almost everyone who takes them and they are causing more harm than any other class of medications. In fact, statins are effective for approximately 1% who take them. In other words, statins fail 99% who take them”

 

 “Serotonin reuptake inhibitors may also alter T4 requirements. In nine patients receiving thyroxine therapy, an elevation in thyrotropin levels and a reduction in FT4 levels were noted after the addition of sertraline hydrochloride.” Gittoes NJ, Franklyn JA. Drug-induced thyroid disorders. Drug Saf 1995; 13:46-55. [PubMed]

 

“Several medications, including iron, aluminum-containing products (such as sucralfate, antacids, and didanosine), ferrous fumerate, sodium polystyrene sulfonate, resin binders, and calcium carbonate have been reported to impair the absorption of exogenous thyroxine and decrease its efficacy.”

– Schneyer CR. Calcium carbonate and reduction of levothyroxine efficacy [letter]. JAMA 1998;279:750. [PubMed]

– Campbell NR, Hasinoff BB, Stalts H, et al. Ferrous sulfate reduces thyroxine efficacy in patients with hypothyroidism. Ann Intern Med 1992;117:1010-1013. [PubMed]

– Liel Y, Sperber AD, Shany S. Nonspecific intestinal adsorption of levothyroxine by aluminum hydroxide. Am J Med 1994;97:363-365. [PubMed]

 

“Hypothyroidism and subclinical hypothyroidism have been reported in 5% to 20% and as high as 50% of people taking lithium carbonate. A twofold increase in the incidence of thyroid antibodies has been found in patients treated with lithium (24%) compared with those not taking lithium (12%). Lithium-induced hypothyroidism is more frequent in those taking lithium for more than 2 years.”

From Kleiner J, Altshuler L, Hendrick V, et al. Lithium-induced subclinical hypothyroidism: review of the literature and guidelines for treatment. J Clin Psychiatry 1999;60:249-255. [PubMed]

 

“Therefore, normal FT4 and T3 levels in a patient taking amiodarone are highly suggestive of overt thyroid dysfunction.” AND “Propranolol hydrochloride (>160 mg/d), atenolol, and metoprolol tartrate produce small reductions in total T3 levels.” from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1070767/treating

 

“Large doses of corticosteroids (for example, >4 mg dexamethasone) produce reductions in total T3 levels, which are useful in the management of thyroid storm or severe hyperthyroidism.” Effects of commonly prescribed nonsteroidal anti-inflammatory drugs on thyroid hormone measurements.  Bishnoi A, Carlson HE, Gruber BL, et al. Effects of commonly prescribed nonsteroidal anti-inflammatory drugs on thyroid hormone measurements. Am J Med 1994;96:235-238.

 

“Thyroid dysfunction is common after interferon alpha therapy for chemotherapy or long-term treatment of hepatitis C. Hypothyroidism is more common (40%-50% of patients) than hyperthyroidism (10%-30% of patients).”

Schwid SR, Goodman AD, Mattson DH. Autoimmune hyperthyroidism in patients with multiple sclerosis treated with interferon beta-1b. Arch Neurol 1997;54:1169-1170. [PubMed].

 

“Cytochrome P-450 hepatic enzyme inducers (for example, rifampin, rifabutin, phenytoin, carbamazepine, and phenobarbital) can increase the metabolic elimination of T4 and T3 by 20%”

– From Stevenson HP, Pooler G, Archbold R, et al. Misleading serum free thyroxine results during low molecular weight heparin treatment. Clin Chem 1998;44:1002-1007.

 

CHEMICALS / PESTICIDES / HEAVY METALS

Heavy metals may be directly linked to the onset and development of Diabetes in this clinical study, in particular arsenic, cadmium and lead,

Perchlorates can cause Hypothyroidism by Pharmacist Suzy Cohen “This pervasive toxin attacks thyroid function. Thyroid hormone gives you energy, improves mood, regulates heart rhythm, stimulates hair growth and helps you burn fat. 

When you drink or eat contaminated foods with perchlorates, they compete with iodine preventing uptake, and this reduces thyroid function. We know for a fact perchlorates inhibit the “sodium-iodide symporter” and perchlorates are sometimes injected intravenously into people in order to test them for Hashimoto’s thyroiditis”

Copper Toxicity and Deficiency “Many adjustments you can make in your life, can have a profound effect in minimizing your copper related symptoms.  Avoiding the primary sources of copper from foods and the environment is always a great start. Limiting your exposure will make you feel so much better if you have high levels or increasing them if your levels are very low.  So, if you are not sure what your levels are, but suspect you have an issue with copper – you need to get it checked”

Why Good Water Filters = Healthier Thyroids! “In order to maintain adequate hydration of the body, our cells and tissues require pure water, free from chemicals and toxins. Standard drinking tap water is likened to a chemical cocktail of harmful, destructive components that do little for our hydration or state of overall health. One of the most detrimental effects these chemicals can have is creating thyroid dysfunction

 

FATS / OILS / CHOLESTEROL

Effects of Thyroid dysfunction on lipid profile Published online 2011 Feb 24 “Thyroid dysfunction has a great impact on lipids as well as a number of other cardiovascular risk factors. Hypothyroidism is relatively common and is associated with an unfavorable effect on lipids. Substitution therapy is beneficial for patients with overt hypothyroidism, improving lipid profile. However, whether subclinical hypothyroidism should be treated or not is a matter of debate. On the other hand, hyperthyroidism can be associated with acquired hypocholesterolemia or unexplained improvement of lipid profile. Overall, thyroid dysfunction should be taken into account when evaluating and treating dyslipidemic patients.”

grass fed beef

Grass fed beef: Clinical data showing increased carotenoids, and lower bad fats. These modern trends aren’t made up facts from a random blogger. Grass fed meat really does contain higher nutritional value and lower health risks. Other articles on this topic include those by the Mayo Clinic and Chris Kresser.

 

The Skinny on Fats, book by Dr David Brownstein “Brownstein and Shenefelt challenge the dietary misinformation of our age – that cholesterol and animal fats are bad for us – in this well organized and easy to understand book. ‘The Skinny on Fats’ will enlighten and educate, and will help you overcome your fear of good fats like butter, cream, egg yolks and lard. Highly recommended.” ~ Sally Fallon Morell, President, The Weston A. Price Foundation

 

MTHRF Gene Mutation Resources

http://ghr.nlm.nih.gov/gene/MTHFR

http://www.stopthethyroidmadness.com/mthfr/

Dr Ben Lynch on MTHFR Genetic Variance and Methylation Wednesday, July 18, 2012

Methionine Deficiency Symptoms  | By Don Amerman

 

 

 

ABOUT THE AUTHOR:

EDITED KIM

Kimberly Orbons

Adv Dip Naturopathy, Adv Dip Western Herbal Medicine

Head Naturopath Kimberly Orbons is passionate about encouraging and empowering each person to facilitate their own good health with Nutrition, Herbal Medicine and preventative lifestyle management. Using a combination of diagnostics and symptomatology to identify the different metabolic processes contributing to disease allows her to treat the root or cause of poor health, providing relief of symptoms and long term recovery.

Kimberly believes it is extremely important to build a personalized healing plan, taking all the complexities of a patient’s health and illness into consideration. Her consults have a strong focus on client care and treating each patient as an individual, and may therefore co-ordinate with other medical treatments. The goal is to establish each patient’s ability to live in the best possible state of health, naturally. Her mentors in clinical practice include Founder Lucy Herron, Dr. David Brownstein, Naturopath Angela Hywood and Dr. Sarah Wine. Since achieving her qualifications in 2007 she has extensive clinical experience, and also 3 years managing the natural health sections and seminar within pharmacy.

Kimberly works closely with our CEO Lizzy Herron and all The Lucy Rose clinical staff to ensure our patients are provided with the best and most up to date health services and quality health advice. She has actively contributed to our online media, patient guidelines, patient support and informational services for the past 3 years and enjoys providing excellent free to access health data to patients across Australia daily.