• Shop For Gift Certificates
  • Book Now
  • Call Us: 123-123-1234
Call Us1300 THYROID (1300 849 764)
HealthHub Login
Free Consult
Call Us1300 THYROID (1300 849 764)
The Lucy Rose Clinic The Lucy Rose Clinic
  • Home
  • Our Approach
    • FAQ
    • Thyroid Practitioners
    • Discover the Thyroid Gland
    • Testing
    • Locations
  • Reviews
  • Conditions
    • Thyroid Nodules
    • Graves’ Disease
    • Hashimoto’s Disease
    • Thyroid and Fertility
    • Thyroid Cancer
    • Thyroid Testing
  • Podcast
  • Articles
  • Contact Us

How your Liver affects THYROID HORMONES​

You are here: Home / Hormones / How your Liver affects THYROID HORMONES​

How your Liver affects THYROID HORMONES​

May 21, 2020January 19, 2022by The Lucy Rose Clinicin Hormones, Liver health, Thyroid Conditions, Weight LossTags hormones, weight loss

Have you been told that your thyroid is ‘normal’ yet you are living with symptoms such as fatigue, mood swings, low libido, and weight gain?

A simple TSH test can miss so much when it comes to thyroid!

Today I want to explain why, and what your liver has to with it.

>>> Check you signs and symptoms below to see if you could be in this boat.

 

Why the liver sometimes fails

There are actually many reasons why thyroid hormone conversion can be suboptimal.

The majority of conversion of T4 to active T3 happens in the liver and kidneys, and then some will also happen in the gastrointestinal-tract and peripheral tissues, and at the blood-brain-barrier.

It is dependant on these systems working well, and having access to the needed nutritional co-factors, as well as good enzyme function.

Enzymes – they make it all happen

Enzymes are proteins that act as biological catalysts. I think of them as the work men at a building site. Hormones are the mortar and vitamins are the bricks – if you get my drift.

Three enzymes catalysing deiodination (converting thyroid hormones) have been identified, called type 1 (D1), type 2 (D2) and type 3 (D3) iodothyronine deiodinases. D1 is largely expressed in liver and kidney. Its main role is clearance of rT3 from the circulation and it also contributes to production of plasma T3.

These vital enzymes are affected by patho-physiological conditions such iodine insufficiency, thyroidal and non-thyroidal illness and malnutrition.

There are several drugs that affect the function of these enzymes resulting in low active thyroid hormone circulation, yet stable TSH. These drugs include PTU (treats hyper thyroid), dexamethasone, propranolol and radiated iodine contrast used for imaging.

Glucuronidation and Fatty Liver

Glucuronidation is a phase II metabolic reaction that increases the water-solubility of endogenous and exogenous compounds to increase their biliary or urinary excretion.

Basically, it a reaction that occurs to eliminate unwanted elements from our system, such as drugs, pollutants, estrogens, androgens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.

If this process is not working well, or is too taxed to work efficiently, it a can lead to a build up of toxins and fat in the liver. When we are wanting to lose weight, we need this to be working well for us, and reducing chemical exposure is a great assistance to the burden on the body.

Sulfation – keeps your liver squeaky clean

In addition to environmental toxins, sulfation is also used to detoxify some normal body chemicals and is the main pathway for the elimination of steroid hormones, thyroid hormones, neurotransmitters and in the elimination of toxins from intestinal bacteria.

Sulforaphane – from broccoli sprout extract – induces phase 2 proteins to conjugate estrogens, remove chemical carcinogens and quench reactive intermediates and reactive oxygen species.

EnduraCell contains the most bio-available Sulforaphane in supplemental form, and is one ingredient in our product Primergene – only available to active Lucy Rose patients.

Nutritional Co-Factors

The liver will need access to nutrients as needed in order to run efficiently.

Selenium is the major cofactor for D1 enzyme activity, and studies have proved that people on a selenium deficient diet have a significant decrease in serum T3.

Levels of selenium varies in different tissues of the body, and dietary intake in the population in Australia is typically low due to low selenium stores in the soil where our food is grown.

Zinc. It has been shown that low zinc status compromises T3 production. Studies have also demonstrated that zinc supplementation improves thyroid hormone production. These effects may be due to the cofactor role zinc plays with D1 enzyme activity.

The Clincher

All the above can be happening, but the pituitary gland doesn’t see it. This means that the feedback loop that allows our body to self regulate hormones is somewhat broken.

This is why you can have a normal TSH level and still have a thyroid problem!

Boom! (mic drop)

Plus it is a self perpetuating issue, because low T3 slows down liver detoxification pathways. It’s a catch 22!

This is why a liver detox is so important for our hormone health, our metabolism, and our weight loss. Are you ready to work with a team who is specially trained to deal with hormone imbalance, weight loss and detoxification based on individual pathology and symptom picture? Then click the button and book your first appointment 🙂


Book your first 15 minute consult FREE!

Signs that your liver is not converting thyroid hormones well:

~ Fatigue – sluggish

~ Waking between 1:00 – 3:00am

~ Low libido

~ Weaker and flabbier muscles

~ Weight gain

~ Poor digestion

~ Thinning hair, shedding hair or hair loss

~ Headaches

~ Puffy eyes, hands or feet

 

Other Factors

The Liver is one BIG part of your health, but it’s not usually the only system out of balance. Depending on your current health picture, we run pathology testing to cover what is needed to get your hormones back into balance.

When testing, we also look at the following factors;

* Nutrient deficiencies or excesses

* Thorough thyroid hormone testing

* Sex hormone balance – E1, E2, E3, Progesterone, Testosterone.

* Cardiovascular risk markers

* Inflammatory Markers

* Food intolerances

* Methylation factors and detoxification capacity.

When you work with a Lucy Rose Practitioner, you work with a TEAM of hand picked and specially up-skilled naturopaths.

Most people on a Lucy Rose program meet their goals in 12 weeks!

Feel free to book a call in with one of my specially trained naturopath practitioners to find out more about our unique approach to wellness. Click here

References:

Home

https://www.amjmed.com/article/S0002-9343(80)80003-9/pdf

https://www.ncbi.nlm.nih.gov/books/NBK285545/

https://restorativemedicine.org/journal/peripheral-thyroid-hormone-conversion-and-its-impact-on-tsh-and-metabolic-activity/

0Comprehensive Thyroid Assessment – Functional TestingPaleo Lasagna

Share this post?

Facebook Twitter Pinterest

About author

The Lucy Rose Clinic

More posts

  • Related
  • Popular
  • Latest
What Causes Beer Belly?
What Causes Beer Belly?
Histamine Intolerance - Is it histamine, allergies or estrogen?
Histamine Intolerance - Is it histamine, allergies or estrogen?
How To Reduce Stress To Lose Weight
How To Reduce Stress To Lose Weight
Is Coffee Bad For You? Coffee Health Benefits and Risks
Is Coffee Bad For You? Coffee Health Benefits and Risks
Is Iodine the Key to Weight Loss? Pt1 - Iodine & Weight Loss
Is Iodine the Key to Weight Loss? Pt1 - Iodine & Weight Loss
The Root Cause to Autoimmune Thyroiditis
The Root Cause to Autoimmune Thyroiditis
Let’s talk about Hydration and Salt! Why you can’t live without it!
Let’s talk about Hydration and Salt! Why you can’t live without it!
Vaccines and Immunity
Vaccines and Immunity
Endometriosis Treatment – Managing Endometriosis
Endometriosis Treatment – Managing Endometriosis
Prostate Health – Keeping a Healthy Prostate
Prostate Health – Keeping a Healthy Prostate
What Causes Beer Belly?
What Causes Beer Belly?
Healing Sweet Potato Soup
Healing Sweet Potato Soup

Search

Recent Podcast

  • The Thyroid and Menopause Complication
    April 4, 2022 by The Lucy Rose Clinic
  • Belly Fat - The Why and How Behind It
    March 14, 2022 by The Lucy Rose Clinic
  • #5 The Role Of The Liver In Optimal Wellness
    March 7, 2022 by The Lucy Rose Clinic
  • #3 Iodine Dosing misconceptions and safe use for thyroid health
    February 28, 2022 by The Lucy Rose Clinic
  • The REAL Reason You Have Brain Fog
    February 23, 2022 by The Lucy Rose Clinic

Categories

  • Autoimmune
  • Beauty
  • Complementary Practices
  • Conditions
  • Detoxification
  • Diagnosis & Testing
  • Fatigue
  • General Knowledge
  • Gut Health
  • Healing Diet
  • Hormones
  • Libido
  • Lifestyle
  • Liver health
  • Medication
  • Mens Hormone Health
  • Mental Health
  • Mood
  • Nodules & Growths
  • Nutrition
  • Patient Stories
  • Podcast
  • Quizzes & Questionnaires
  • Recipes
  • Sleep
  • Stress hormones
  • Supplements
  • Thyroid
  • Thyroid Conditions
  • Uncategorized
  • Vitality Boosting Programs
  • Vlog
  • Weight Loss

Follow Us

Recent Posts

  • Endometriosis Treatment – Managing Endometriosis
  • Prostate Health – Keeping a Healthy Prostate
  • What Causes Beer Belly?
  • Healing Sweet Potato Soup
  • Irritable Bowel Syndrome and Thyroid
Contact Info
Sydney CBD (Head Office), Suite 13, level 3, 247 Coward St. Mascot NSW 2020
1300 THYROID (1300 849 764)
info@thelucyroseclinic.com.auEmail Us
Contact Us
Open Hours
  • Monday 9am-5pm
  • Tuesday 9am-5pm
  • Wednesday 9am-5pm
  • Thrusday 9am-5pm
  • Friday 9am-5pm
Contact Us
Latest Articles
  • Endometriosis Treatment – Managing Endometriosis
  • Prostate Health – Keeping a Healthy Prostate
  • What Causes Beer Belly?
  • Healing Sweet Potato Soup
  • Irritable Bowel Syndrome and Thyroid
  • The Effect of Iodine on Testosterone in Men
  • 7 Home Remedies for Cold and Flu Symptoms
  • What Causes Bumpy Arm Skin (or Keratosis Pilaris)?
  • Graves Disease in Men
  • Vegan Cheese Sauce
View More
Quick Links
  • Our Approach
  • FAQ
  • About Thyroid
  • Testing
  • Reviews
  • Articles
  • Contact Us
© 2020 The Lucy Rose Clinic. All Rights Reserved - Terms & Conditions - Privacy Policy
The Lucy rose clicnic

Privacy Policy. Visit Our Website.

Talk To Us Today - Click Here To Book An Appointment To Talk To An Experienced Practitioner

The Lucy Rose Clinic - Sydney CBD (Head Office), Suite 13, Level 1, 110 Sussex St, Sydney, NSW, 2000 - 1300 849 764

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Cookie settingsACCEPT
Privacy & Cookies Policy

Privacy Overview

This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.
Necessary
Always Enabled
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Non-necessary
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.
SAVE & ACCEPT